Emergency services responded to reports that a vehicle had crashed into a tree along Forest Road, Comberton just after midday on Thursday January 8.
The driver and sole occupant a 46-year-old man, was trapped in the car until released by rescue personnel.
He was treated at the scene by NSW Ambulance paramedics and airlifted to St George Hospital in a serious but stable condition.
Officers from Nowra Highway Patrol have commenced an investigation into the matter.
As inquiries continue police are urging anyone who may have witnessed the incident or has any available dash cam footage to contact Crime Stoppers on 1800 333 000.